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اثر تمرین هوازی روی تردمیل بر سطوح آدیپولین، گلوکز و انسولین در رتهای نر دیابتی نوع 2 | ||
| مطالعات کاربردی تندرستی در فیزیولوژی ورزش | ||
| مقاله 12، دوره 5، شماره 1، فروردین 1397، صفحه 93-105 اصل مقاله (526.46 K) | ||
| نوع مقاله: مقاله پژوهشی Released under (CC BY-NC 4.0) license I Open Access I | ||
| شناسه دیجیتال (DOI): 10.22049/jassp.2019.26571.1238 | ||
| نویسندگان | ||
| رحیم رحیم پور1؛ جواد مهربانی* 2 | ||
| 1کارشناس ارشد فیزیولوژی ورزشی، دانشکده تربیت بدنی و علوم ورزشی دانشگاه گیلان، رشت، ایران | ||
| 2استادیار گروه فیزیولوژی ورزش، دانشکده تربیت بدنی و علوم ورزشی دانشگاه گیلان، رشت، ایران. | ||
| چکیده | ||
| Secretion of pro-inflammatory and anti-inflammatory cytokines play a critical role in the regulation of metabolic conditions. This study examines the effect of eight weeks aerobic training on Adipolin cytokine and insulin resistance index in type 2 diabetic male rats. Eighteen 8-10 weeks Wister rats with 200-220 gr are selected and they divided equaly into two diabetes [DBT] and control [CON] groups randomly. The training program includes 8 weeks of endurance training on a treadmill at a constant dip of 5%. The speed started from 10 meters per minute and it rised to the 25 meters per minute and its time started from 15 minutes to 45 minutes. In end of 8 weeks training, blood samples were taken after 12 hours of fasting in order to determination of insulin, glucose and Adipulin levels. The homeostatic model assessment [HOMA] was calculated as insulin resistance index. The data were analyzed using the an independent t test with the SPSS software ver. 16. A meaningful increase was observed in adipolin (1.36±0.054 vs. 1.11±0.065 ng/ml; p=0.002), and decrease in glucose (276.88±27.59 vs. 324.55±16.04 mg/dl; p=0.001), insulin (0.206±0.02 vs. 0.235±0.02 mU/l; p=0.033) and insulin resistance (2.55±0.495 vs. 3.40±0.468 mg/dl; p=0.002). According to the findings, it seems that aerobic training with moderate intensity will lead to decreasing in insulin resistance and increase in serum levels of Adipulin in type 2 diabetic rats. | ||
| کلیدواژهها | ||
| تمرین هوازی؛ آدیپولین؛ مقاومت به انسولین؛ دیابت نوع 2 | ||
| مراجع | ||
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