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احمدآبادی, فرشته, ثاقب جو, مرضیه. (1401). نقش تمرینات ورزشی با شدت متوسط و بالا در پیشگیری و درمان سرطان پستان: یک مرور سیستماتیک. , 9(2), 149-172. doi: 10.22049/jahssp.2022.27939.1488
فرشته احمدآبادی; مرضیه ثاقب جو. "نقش تمرینات ورزشی با شدت متوسط و بالا در پیشگیری و درمان سرطان پستان: یک مرور سیستماتیک". , 9, 2, 1401, 149-172. doi: 10.22049/jahssp.2022.27939.1488
احمدآبادی, فرشته, ثاقب جو, مرضیه. (1401). 'نقش تمرینات ورزشی با شدت متوسط و بالا در پیشگیری و درمان سرطان پستان: یک مرور سیستماتیک', , 9(2), pp. 149-172. doi: 10.22049/jahssp.2022.27939.1488
احمدآبادی, فرشته, ثاقب جو, مرضیه. نقش تمرینات ورزشی با شدت متوسط و بالا در پیشگیری و درمان سرطان پستان: یک مرور سیستماتیک. , 1401; 9(2): 149-172. doi: 10.22049/jahssp.2022.27939.1488

نقش تمرینات ورزشی با شدت متوسط و بالا در پیشگیری و درمان سرطان پستان: یک مرور سیستماتیک

مطالعات کاربردی تندرستی در فیزیولوژی ورزش
دوره 9، شماره 2، مهر 1401، صفحه 149-172    اصل مقاله (1.39 M)
نوع مقاله: مقاله مروری Released under (CC BY-NC 4.0) license I Open Access I
شناسه دیجیتال (DOI): 10.22049/jahssp.2022.27939.1488
نویسندگان
فرشته احمدآبادی* 1؛ مرضیه ثاقب جو2
1استادیار فیزیولوژی ورزشی، گروه علوم ورزشی، دانشکده علوم ورزشی، دانشگاه کایسر، وست پالم بیچ، آمریکا.
2استاد فیزیولوژی ورزشی، گروه فیزیولوژی ورزشی، دانشکده علوم ورزشی، دانشگاه بیرجند، بیرجند، ایران.
چکیده
هدف: سرطان پستان یک اختلال ناشی از رشد نامنظم سلول­ها در بافت پستان است که به­طور قابل توجهی در سراسر جهان افزایش یافته است و  در حال حاضر شایع‌ترین تشخیص سرطان در زنان می­باشد. هدف از پژوهش حاضر، مروری سیستماتیک روی مطالعات انجام شده جهت بررسی تأثیر تمرینات ورزشی با شدت متوسط و بالا بر پیشگیری و درمان سرطان پستان می­باشد. روش شناسی: جستجوی مقالات مربوط به نقش تمرینات ورزشی در پیشگیری و درمان سرطان پستان و مسیرهای مولکولی درگیر در آن در پایگاه­های اطلاعاتی معتبر از جملهPub Med, Google Scholar, Scopus, SID,  وISC بین سال­های 2000 تا 2021 انجام گرفت. یافته­ها: در مطالعات مربوط به تأثیر تمرینات ورزشی در پیشگیری از سرطان پستان در افراد با خطر بالای ابتلا به سرطان پستان، نتایج نشان داد زنانی که سطح بالایی از فعالیت بدنی را دارند، 20 درصد کمتر از زنان با سطوح پایین فعالیت ورزشی به سرطان پستان مبتلا می­شوند. یافته­ها در ارتباط با تأثیر تمرینات ورزشی بر کنترل پیشرفت سرطان پستان، حاکی از آن است که تمرینات ورزشی به­طور مستقیم از طریق تأثیر روی عوامل درونی تومور و سازوکارهای مولکولی، موجب کنترل و یا بهبود سرطان پستان بدون هیچ عارضه جانبی می­شود. نتیجه­گیری: تمرینات ورزشی را می­توان به­عنوان یک مداخله مهم در پیشگیری و مکمل درمان سرطان پستان از طریق مهار تکثیر سلول­های سرطانی، القاء آپوپتوز، سرکوب آنژیوژنز، تنظیم محیط التهابی و بهبود عوارض ناشی از درمان سرطان در نظر گرفت.   
کلیدواژه‌ها
سرطان پستان؛ آپوپتوز؛ التهاب سیستمیک؛ آنژیوژنز؛ تمرینات ورزشی
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