دانشگاه شهید مدنی آذربایجان

 آمار

تعداد نشریات6
تعداد شماره‌ها131
تعداد مقالات1,634
تعداد مشاهده مقاله1,899,074
تعداد دریافت فایل اصل مقاله1,758,848
احمدآبادی, فرشته, ثاقب جو, مرضیه. (1401). نقش تمرینات ورزشی با شدت متوسط و بالا در پیشگیری و درمان سرطان پستان: یک مرور سیستماتیک. , 9(2), 149-172. doi: 10.22049/jahssp.2022.27939.1488
فرشته احمدآبادی; مرضیه ثاقب جو. "نقش تمرینات ورزشی با شدت متوسط و بالا در پیشگیری و درمان سرطان پستان: یک مرور سیستماتیک". , 9, 2, 1401, 149-172. doi: 10.22049/jahssp.2022.27939.1488
احمدآبادی, فرشته, ثاقب جو, مرضیه. (1401). 'نقش تمرینات ورزشی با شدت متوسط و بالا در پیشگیری و درمان سرطان پستان: یک مرور سیستماتیک', , 9(2), pp. 149-172. doi: 10.22049/jahssp.2022.27939.1488
احمدآبادی, فرشته, ثاقب جو, مرضیه. نقش تمرینات ورزشی با شدت متوسط و بالا در پیشگیری و درمان سرطان پستان: یک مرور سیستماتیک. , 1401; 9(2): 149-172. doi: 10.22049/jahssp.2022.27939.1488

نقش تمرینات ورزشی با شدت متوسط و بالا در پیشگیری و درمان سرطان پستان: یک مرور سیستماتیک

مطالعات کاربردی تندرستی در فیزیولوژی ورزش
دوره 9، شماره 2، مهر 1401، صفحه 149-172    اصل مقاله (1.39 M)
نوع مقاله: مقاله مروری Released under (CC BY-NC 4.0) license I Open Access I
شناسه دیجیتال (DOI): 10.22049/jahssp.2022.27939.1488
نویسندگان
فرشته احمدآبادی* 1؛ مرضیه ثاقب جو2
1استادیار فیزیولوژی ورزشی، گروه علوم ورزشی، دانشکده علوم ورزشی، دانشگاه کایسر، وست پالم بیچ، آمریکا.
2استاد فیزیولوژی ورزشی، گروه فیزیولوژی ورزشی، دانشکده علوم ورزشی، دانشگاه بیرجند، بیرجند، ایران.
چکیده
هدف: سرطان پستان یک اختلال ناشی از رشد نامنظم سلول­ها در بافت پستان است که به­طور قابل توجهی در سراسر جهان افزایش یافته است و  در حال حاضر شایع‌ترین تشخیص سرطان در زنان می­باشد. هدف از پژوهش حاضر، مروری سیستماتیک روی مطالعات انجام شده جهت بررسی تأثیر تمرینات ورزشی با شدت متوسط و بالا بر پیشگیری و درمان سرطان پستان می­باشد. روش شناسی: جستجوی مقالات مربوط به نقش تمرینات ورزشی در پیشگیری و درمان سرطان پستان و مسیرهای مولکولی درگیر در آن در پایگاه­های اطلاعاتی معتبر از جملهPub Med, Google Scholar, Scopus, SID,  وISC بین سال­های 2000 تا 2021 انجام گرفت. یافته­ها: در مطالعات مربوط به تأثیر تمرینات ورزشی در پیشگیری از سرطان پستان در افراد با خطر بالای ابتلا به سرطان پستان، نتایج نشان داد زنانی که سطح بالایی از فعالیت بدنی را دارند، 20 درصد کمتر از زنان با سطوح پایین فعالیت ورزشی به سرطان پستان مبتلا می­شوند. یافته­ها در ارتباط با تأثیر تمرینات ورزشی بر کنترل پیشرفت سرطان پستان، حاکی از آن است که تمرینات ورزشی به­طور مستقیم از طریق تأثیر روی عوامل درونی تومور و سازوکارهای مولکولی، موجب کنترل و یا بهبود سرطان پستان بدون هیچ عارضه جانبی می­شود. نتیجه­گیری: تمرینات ورزشی را می­توان به­عنوان یک مداخله مهم در پیشگیری و مکمل درمان سرطان پستان از طریق مهار تکثیر سلول­های سرطانی، القاء آپوپتوز، سرکوب آنژیوژنز، تنظیم محیط التهابی و بهبود عوارض ناشی از درمان سرطان در نظر گرفت.   
کلیدواژه‌ها
سرطان پستان؛ آپوپتوز؛ التهاب سیستمیک؛ آنژیوژنز؛ تمرینات ورزشی
مراجع
  1. 1. Reuter-Lorenz PA, Cimprich B. Cognitive function and breast cancer: promise and potential insights from functional brain imaging. Breast cancer research and treatment. 2013;137(1):33-43.
  2. 2. McTiernan A, Kooperberg C, White E, Wilcox S, Coates R, Adams-Campbell LL, et al. Recreational physical activity and the risk of breast cancer in postmenopausal women: the Women's Health Initiative Cohort Study. Jama. 2003;290(10):1331-6.
  3. 3. Niemiro GM, Coletta AM, Agha NH, Mylabathula PL, Baker FL, Brewster AM, et Salutary effects of moderate but not high intensity aerobic exercise training on the frequency of peripheral T-cells associated with immunosenescence in older women at high risk of breast cancer: a randomized controlled trial. 2021.
  4. 4. Ahmadabadi F, Saghebjoo M, Huang C-J, Saffari I, Zardast M. The effects of high-intensity interval training and saffron aqueous extract supplementation on alterations of body weight and apoptotic indices in skeletal muscle of 4T1 breast cancer-bearing mice with cachexia. Applied Physiology, Nutrition, and Metabolism. 2020;45(5):555-63.
  5. 5. Hojman P, Gehl J, Christensen JF, Pedersen BK. Molecular mechanisms linking exercise to cancer prevention and treatment. Cell Metabolism. 2018;27(1):10-21.
  6. 6. JB SG, Silva-Filho A, Dias C, Leite R, Mostarda C. Effect of exercise training and detraining in autonomic modulation and cardiorespiratory fitness in breast cancer survivors. The Journal of Sports Medicine and Physical Fitness. 2017;57(7-8):1062-8.
  7. 7. Volaklis KA, Halle M, Tokmakidis SP. Exercise in the prevention and rehabilitation of breast cancer. Wiener klinische Wochenschrift. 2013;125(11):297-301.
  8. 8. Teoh SL, Das S. Tumour biology of obesity-related cancers: understanding the molecular concept for better diagnosis and treatment. Tumor Biology. 2016;37(11):14363-80.
  9. 9. Wang Y, Lam KS, Xu A. Adiponectin as a negative regulator in obesity-related mammary carcinogenesis. Cell Research. 2007;17(4):280-2.
  10. 10. Nezamdoost Z, Saghebjoo M, Hoshyar R, Hedayati M, Keska A. High-Intensity Training and Saffron: Effects on Breast Cancer-related Gene Expression. Medicine and Science in Sports and Exercise. 2020.
  11. 11. Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, et al. Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA: A Cancer Journal for Clinicians. 2021;71(3):209-49.
  12. 12. Bray F, Laversanne M, Weiderpass E, Soerjomataram I. The ever‐increasing importance of cancer as a leading cause of premature death worldwide. Cancer. 2021.
  13. 13. Ferlay J, Colombet M, Soerjomataram I, Parkin DM, Piñeros M, Znaor A, et al. Cancer statistics for the year 2020: An overview. International Journal of Cancer. 2021.
  14. 14. DeSantis C, Ma J, Bryan L, Jemal A. Breast cancer statistics, 2013. CA: a cancer journal for clinicians. 2014;64(1):52-62.
  15. 15. Motovali-Bashi M, Amirmahani F, Ghatre Samani Z. Association between miR-152/148a polymorphisms and age of onset and progression of breast cancer in Isfahan population. Research in Medicine. 2017;40(4):187-91.
  16. 16. Daly AA, Rolph R, Cutress RI, Copson ER. A Review of Modifiable Risk Factors in Young Women for the Prevention of Breast Cancer. Breast Cancer: Targets and Therapy. 2021;13:241.
  17. 17. Kazemi A, Mirza-zade E. The Effect of Endurance Training on Tumor Tissue Levels of Caspase-3 and Caspase-9 in Mice with Breast Cancer. Iranian Quarterly Journal of Breast Disease. 2018;11(3):32-43. [In Persian].
  18. 18. Mills III RC. Breast cancer survivors, common markers of inflammation, and exercise: a narrative review. Breast cancer: basic and clinical research. 2017;11:1178223417743976.
  19. 19. Pecorino L. Molecular biology of cancer: mechanisms, targets, and therapeutics: Oxford university press; 2012.
  20. 20. Galvão DA, Newton RU. Review of exercise intervention studies in cancer patients. Journal of Clinical Oncology. 2005;23(4):899-909.
  21. 21. Lopez P, Galvão DA, Taaffe DR, Newton RU, Souza G, Trajano GS, et al. Resistance training in breast cancer patients undergoing primary treatment: a systematic review and meta-regression of exercise dosage. Breast Cancer. 2021;28(1):16-24.
  22. 22. Wang Q, Zhou W. Roles and molecular mechanisms of physical exercise in cancer prevention and treatment. Journal of Sport and Health Science. 2021;10(2):201-10.
  23. 23. Ashcraft KA, Warner AB, Jones LW, Dewhirst MW, editors. Exercise as adjunct therapy in cancer. Seminars in radiation oncology; 2019: Elsevier.
  24. 24. Johnsson A, Demmelmaier I, Sjövall K, Wagner P, Olsson H, Tornberg ÅB. A single exercise session improves side-effects of chemotherapy in women with breast cancer: an observational study. BMC cancer. 2019;19(1):1-9.
  25. 25. Ahmadabadi F, Saghebjoo M, Hedayati M, Hoshyar R, Huang C-J. Treatment-induced tumor cell apoptosis following high-intensity interval training and saffron aqueous extract in mice with breast cancer. Physiology International. 2021;108(1):19-26.
  26. 26. Meyerhardt JA, Giovannucci EL, Holmes MD, Chan AT, Chan JA, Colditz GA, et al. Physical activity and survival after colorectal cancer diagnosis. Journal of clinical 2006;24(22):3527-34.
  27. 27. Saedmocheshi S, Saghebjoo M, Vahabzadeh Z, Sheikholeslami-Vatani D. Aerobic Training and Green Tea Extract Protect against N-methyl-N-nitrosourea-induced Prostate Cancer. Medicine and science in sports and exercise. 2019;51(11):2210-6.
  28. 28. McTiernan A. Mechanisms linking physical activity with cancer. Nature Reviews Cancer. 2008;8(3):205-11.
  29. 29. Ashcraft KA, Peace RM, Betof AS, Dewhirst MW, Jones LW. Efficacy and mechanisms of aerobic exercise on cancer initiation, progression, and metastasis: a critical systematic review of in vivo preclinical data. Cancer research. 2016;76(14):4032-50.
  30. 30. Wijler LA, Raats DA, Verheem A, den Otter AM, Rundqvist H, van Dijk M, et al. Voluntary exercise influences metastatic organotropism in a murine colorectal cancer model. JCSM Rapid Communications. 2021.
  31. 31. Weston KS, Wisløff U, Coombes JS. High-intensity interval training in patients with lifestyle-induced cardiometabolic disease: a systematic review and meta-analysis. Br J Sports Med. 2014;48(16):1227-34.
  32. 32. Devin JL, Sax AT, Hughes GI, Jenkins DG, Aitken JF, Chambers SK, et al. The influence of high-intensity compared with moderate-intensity exercise training on cardiorespiratory fitness and body composition in colorectal cancer survivors: a randomised controlled trial. Journal of cancer survivorship. 2016;10(3):467-79.
  33. 33. Toohey K, Pumpa KL, Arnolda L, Cooke J, Yip D, Craft PS, et al. A pilot study examining the effects of low-volume high-intensity interval training and continuous low to moderate intensity training on quality of life, functional capacity and cardiovascular risk factors in cancer survivors. PeerJ. 2016;4:e2613.
  34. 34. Milanović Z, Sporiš G, Weston M. Effectiveness of high-intensity interval training (HIT) and continuous endurance training for VO 2max improvements: a systematic review and meta-analysis of controlled trials. Sports medicine. 2015;45(10):1469-81.
  35. 35. Thompson WR. Worldwide survey of fitness trends for 2016. ACSMs Health Fit J. 2015;19(6):9-18.
  36. 36. Betof AS, Dewhirst MW, Jones LW. Effects and potential mechanisms of exercise training on cancer progression: a translational perspective. Brain, behavior, and immunity. 2013;30:S75-S87.
  37. 37. Evans ES, Battaglini CL, Groff DG, Hackney A. Aerobic exercise intensity in breast cancer patients: a preliminary investigation. Integrative cancer therapies. 2009;8(2):139-47.
  38. 38. Shamsaei N, Abdi H, Shamsi M. The Effect of a Continuous Training on Necrosis and Apoptosis Changes in the Hippocampus of Diabetic Rats. Journal of Ilam University of Medical Sciences. 2017;25(1):1-11. [In Persian].
  39. 39. Papadopoulos E, Santa Mina D. Can we HIIT cancer if we attack inflammation? Cancer Causes & Control. 2018;29(1):7-11.
  40. 40. Ahmadabadi F, Saghebjoo M, Hoshyar R. Decreased Liver Tissue Wasting following High-Intensity Interval Training through Apoptosis Signaling Suppression in Breast Tumor–Bearing Female Mice. Iranian Quarterly Journal of Breast Disease. 2020;13(2):49-58. [In Persian].
  41. 41. Nezamdoost Z, Saghebjoo M, Hoshyar R, Hedayati M, Sadeghi Tabas S. The Effect of High-Intensity Interval Training and Saffron Extract on the Expression of Some Cachexia-Related Genes in the Skeletal Muscle of Female Mice Carrying Breast Cancer Cell Line. Sport Physiology. 2020;12(48):83-104. [In Persian].
  42. 42. Coletta AM, Brewster AM, Chen M, Li Y, Bevers TB, Basen-Engquist K, et al. High-intensity interval training is feasible in women at high risk for breast cancer. Medicine and science in sports and exercise. 2019;51(11):2193.
  43. 43. Coletta AM, Agha NH, Baker FL, Niemiro GM, Mylabathula PL, Brewster AM, et al. The impact of high-intensity interval exercise training on NK-cell function and circulating myokines for breast cancer prevention among women at high risk for breast cancer. Breast Cancer Research and Treatment. 2021;187(2):407-16.
  44. 44. Lammert J, Lubinski J, Gronwald J, Huzarski T, Armel S, Eisen A, et al. Physical activity during adolescence and young adulthood and the risk of breast cancer in BRCA1 and BRCA2 mutation carriers. Breast Cancer Research and Treatment. 2018;169(3):561-71.
  45. 45. Gonçalves AK, Florêncio GLD, de Atayde Silva MJM, Cobucci RN, Giraldo PC, Cote NM. Effects of physical activity on breast cancer prevention: a systematic review. Journal of Physical Activity and Health. 2014;11(2):445-54.
  46. 46. Santulli G, Iaccarino G. Pinpointing beta adrenergic receptor in ageing pathophysiology: victim or executioner? Evidence from crime scenes. Immunity & Ageing. 2013;10(1):1-13.
  47. 47. Desnoyers A, Riesco E, Fülöp T, Pavic M. Physical activity and cancer: Update and literature La Revue de medecine interne. 2016;37(6):399-405.
  48. 48. Gail MH, Anderson WF, Garcia-Closas M, Sherman ME. Absolute risk models for subtypes of breast cancer. Oxford University Press; 2007. p. 1657-9.
  49. 49. Dyrstad SW, Yan Y, Fowler AM, Colditz GA. Breast cancer risk associated with benign breast disease: systematic review and meta-analysis. Breast cancer research and treatment. 2015;149(3):569-75.
  50. 50. Lauby-Secretan B, Scoccianti C, Loomis D, Grosse Y, Bianchini F, Straif K. Body fatness and cancer—viewpoint of the IARC Working Group. New England Journal of Medicine. 2016;375(8):794-8.
  51. 51. Mohanty SS, Mohanty PK. Obesity as potential breast cancer risk factor for postmenopausal women. Genes & Diseases. 2021;8(2):117-23.
  52. 52. Campbell KL, McTiernan A. Exercise and Biomarkers for Cancer Prevention Studies. The Journal of Nutrition. 2007;137(1):161S-9S.
  53. 53. Kehm RD, Genkinger JM, MacInnis RJ, John EM, Phillips K-A, Dite GS, et al. Recreational physical activity is associated with reduced breast cancer risk in adult women at high risk for breast cancer: a cohort study of women selected for familial and genetic risk. Cancer research. 2020;80(1):116-25.
  54. 54. Kotsopoulos J, Olopade OI, Ghadirian P, Lubinski J, Lynch HT, Isaacs C, et al. Changes in body weight and the risk of breast cancer in BRCA1 and BRCA2 mutation carriers. Breast Cancer Research. 2005;7(5):1-11.
  55. 55. Fackenthal JD, Olopade OI. Breast cancer risk associated with BRCA1 and BRCA2 in diverse populations. Nature Reviews Cancer. 2007;7(12):937-4
  56. 56. Sprague BL, Trentham-Dietz A, Newcomb PA, Titus-Ernstoff L, Hampton JM, Egan KM. Lifetime recreational and occupational physical activity and risk of in situ and invasive breast cancer. Cancer Epidemiology and Prevention Biomarkers. 2007;16(2):236-43.
  57. 57. Bigley AB, Rezvani K, Chew C, Sekine T, Pistillo M, Crucian B, et al. Acute exercise preferentially redeploys NK-cells with a highly-differentiated phenotype and augments cytotoxicity against lymphoma and multiple myeloma target cells. Brain, behavior, and immunity. 2014;39:160-71.
  58. 58. Goh J, Endicott E, Ladiges WC. Pre-tumor exercise decreases breast cancer in old mice in a distance-dependent manner. American journal of cancer research. 2014;4(4):378.
  59. 59. Vulczak A, Souza AdO, Ferrari GD, Azzolini AECS, Pereira-da-Silva G, Alberici LC. Moderate Exercise Modulates Tumor Metabolism of Triple-Negative Breast Cancer. Cells. 2020;9(3):628.
  60. 60. Wennerberg E, Lhuillier C, Rybstein MD, Dannenberg K, Rudqvist N-P, Koelwyn GJ, et al. Exercise reduces immune suppression and breast cancer progression in a preclinical model. Oncotarget. 2020;11(4):452.
  61. 61. Sadeghipoor Vojdani F, Agha-Alinejad H, Molanouri Shamsi M, Soudi S, Khanchi S. The Effect of Interval Training on the Expression of Tumor Suppressor Gene, Systemic Inflammation, and Tumor Volume in Breast Cancer–Bearing BALB/c Mice. Iranian Quarterly Journal of Breast Diseases. 2019;12(3):17-25. [In Persian].
  62. 62. Delphan M, Agha Alinejad H, Delfan M, Dehghan S. Intratumoral Effects of Continuous Endurance Training and High Intensity Interval Training on Genes Expression of miR-21 and bcl-2 in Breast Cancer Bearing Female mice. Iranian Quarterly Journal of Breast Diseases [Persian]. 2017;10(2):49-57. [In Persian].
  63. 63. Nasiri M, Peeri M, Matinhomaee H. The Comparison of HighIntensity Interval Training Versus Continuous Training on the Expression of ErbB3 in Breast Cancer Bearing mice. Iranian Quarterly Journal of Breast Diseases. 2016;9(3):25-30. [In Persian].
  64. 64. Betof AS, Lascola CD, Weitzel D, Landon C, Scarbrough PM, Devi GR, et al. Modulation of murine breast tumor vascularity, hypoxia, and chemotherapeutic response by exercise. JNCI: Journal of the National Cancer Institute. 2015;107. (5).
  65. 65. Wang B, Xu H, Hu X, Ma W, Zhang J, Li Y, et al. Synergetic inhibition of daidzein and regular exercise on breast cancer in bearing-4T1 mice by regulating NK cells and apoptosis pathway. Life Sciences. 2020;245:117387.
  66. 66. Agha-Alinejad H, Hashemi Jokar E. Effect of Six Weeks of Interval Exercise Training along with Selenium Nanoparticle Ingestion on Bcl-2 and LC3 Genes expression in the Tumor Tissue of Breast Tumor–Bearing Mice. Iranian Quarterly Journal of Breast Diseases. 2019;12(2):26-37. [In Persian].
  67. 67. Masoudzade G, Barari A, Amini S. Synergistic Effect of Aloe vera Extract and Aerobic Training on Tumor Weight and Volume and Levels of Interleukin 6 and Vascular Endothelial Growth Factor in Mice with Breast Cancer. Iranian Journal of Breast Diseases. 2019;11(4):17-27. [In Persian].
  68. 68. Siewierska K, Malicka I, Kobierzycki C, Paslawska U, Cegielski M, Grzegrzolka J, et al. The impact of exercise training on breast cancer. in vivo. 2018;32(2):249-54.
  69. 69. Rezaei Z, Shakerian S, Nikbakht M. The Effect of Ten Weeks of High Intensity Interval Training and Continuous Endurance Training on The Expression of MIR-205 and VEGF Gene in Mice with Breast Cancer Has Been Compared. Journal of Applied Health Studies in Sport Physiology. 2019;6(1):37-44. [In Persian].
  70. 70. Courneya K, Friedenreich C, Quinney H, Fields A, Jones L, Fairey A. A randomized trial of exercise and quality of life in colorectal cancer European journal of cancer care. 2003;12(4):347-57.
  71. 71. Segal RJ, Reid RD, Courneya KS, Sigal RJ, Kenny GP, Prud'Homme DG, et al. Randomized controlled trial of resistance or aerobic exercise in men receiving radiation therapy for prostate cancer. Journal of clinical oncology. 2009;27(3):344-51.
  72. 72. Higgins KA, Park D, Lee GY, Curran WJ, Deng X. Exercise‐induced lung cancer regression: Mechanistic findings from a mouse model. Cancer. 2014;120(21):3302-10.
  73. 73. Van Vulpen JK, Peeters PH, Velthuis MJ, Van Der Wall E, May AM. Effects of physical exercise during adjuvant breast cancer treatment on physical and psychosocial dimensions of cancer-related fatigue: a meta-analysis. Maturitas. 2016;85:104-11.
  74. 74. Hojman P. Exercise protects from cancer through regulation of immune function and inflammation. Biochemical Society Transactions. 2017;45(4):905-11.
  75. 75. Adams SC, DeLorey DS, Davenport MH, Stickland MK, Fairey AS, North S, et al. Effects of high‐intensity aerobic interval training on cardiovascular disease risk in testicular cancer survivors: A phase 2 randomized controlled trial. Cancer. 2017;123(20):4057-65.
  76. 76. Hwang C-L, Yu C-J, Shih J-Y, Yang P-C, Wu Y-T. Effects of exercise training on exercise capacity in patients with non-small cell lung cancer receiving targeted therapy. Supportive care in cancer. 2012;20(12):3169-77.
  77. 77. Kampshoff CS, Chinapaw MJ, Brug J, Twisk JW, Schep G, Nijziel MR, et al. Randomized controlled trial of the effects of high intensity and low-to-moderate intensity exercise on physical fitness and fatigue in cancer survivors: results of the Resistance and Endurance exercise After ChemoTherapy (REACT) study. BMC medicine. 2015;13(1):275.
  78. 78. Licker M, Karenovics W, Diaper J, Frésard I, Triponez F, Ellenberger C, et al. Short-term preoperative high-intensity interval training in patients awaiting lung cancer surgery: a randomized controlled trial. Journal of Thoracic Oncology. 2017;12(2):323-33.
  79. 79. Midtgaard J, Christensen JF, Tolver A, Jones L, Uth J, Rasmussen B, et al. Efficacy of multimodal exercise-based rehabilitation on physical activity, cardiorespiratory fitness, and patient-reported outcomes in cancer survivors: a randomized, controlled trial. Annals of oncology. 2013;24(9):2267-73.
  80. 80. Adamsen L, Quist M, Andersen C, Møller T, Herrstedt J, Kronborg D, et al. Effect of a multimodal high intensity exercise intervention in cancer patients undergoing chemotherapy: randomised controlled trial. Bmj. 2009;339:b3410.
  81. 81. Schulz SVW, Laszlo R, Otto S, Prokopchuk D, Schumann U, Ebner F, et al. Feasibility and effects of a combined adjuvant high-intensity interval/strength training in breast cancer patients: a single-center pilot study. Disability and Rehabilitation. 2017:1-8.
  82. 82. Schmitt J, Lindner N, Reuss‐Borst M, Holmberg HC, Sperlich B. A 3‐week multimodal intervention involving high‐intensity interval training in female cancer survivors: a randomized controlled trial. Physiological reports. 2016;4(3).
  83. 83. Zielinski MR, Muenchow M, Wallig MA, Horn PL, Woods JA. Exercise delays allogeneic tumor growth and reduces intratumoral inflammation and vascularization. Journal of applied physiology. 2004;96(6):2249-56.
  84. 84. Nasiri M, Peeri M, Matinhomaee H. The Comparison of HighIntensity Interval Training Versus Continuous Training on the Expression of ErbB3 in Breast Cancer Bearing mice. Iranian Journal of Breast Diseases. 2016;9(3):25-30. [In Persian].
  85. 85. Wang S, Huang X, Lee CK, Liu B. Elevated expression of erbB3 confers paclitaxel resistance in erbB2-overexpressing breast cancer cells via upregulation of Survivin. Oncogene. 2010;29(29):4225-36.
  86. 86. Shabani S, Mortazavi, P. . Study of rosemary extract on BCL2 and BAX gene expression in canine mammary gland carcinoma cell line (CF41.Mg). Journal of Comparative Pathobiology. 2017;14(1):2112-05.
  87. 87. Jehn C, Flath B, Strux A, Krebs M, Possinger K, Pezzutto A, et al. Influence of age, performance status, cancer activity, and IL-6 on anxiety and depression in patients with metastatic breast cancer. Breast Cancer Research and Treatment. 2012;136(3):789-94.
  88. 88. Wong RS. Apoptosis in cancer: from pathogenesis to treatment. Journal of Experimental & Clinical Cancer Research. 2011;30(1):87.
  89. 89. Lockshin RA, Zakeri Z. Programmed cell death and apoptosis: origins of the theory. Nature reviews Molecular Cell Biology. 2001;2(7):545.
  90. 90. Danial NN, Korsmeyer SJ. Cell death: critical control points. Cell. 2004;116(2):205-19.
  91. 91. Khori V, Shalamzari SA, Isanejad A, Alizadeh AM, Alizadeh S, Khodayari S, et al. Effects of exercise training together with tamoxifen in reducing mammary tumor burden in mice: Possible underlying pathway of miR-21. European Journal of Pharmacology. 2015;765:179-87.
  92. 92. Pawlowski J, Kraft AS. Bax-induced apoptotic cell death. Proceedings of the national academy of sciences. 2000;97(2):529-31.
  93. 93. Buscaglia LEB, Li Y. Apoptosis and the target genes of microRNA-21. Chinese journal of cancer. 2011;30(6):371.
  94. 94. Barra NG, Fan IY, Gillen JB, Chew M, Marcinko K, Steinberg GR, et al. High intensity interval training increases natural killer cell number and function in obese breast cancer-challenged mice and obese women. Journal of Cancer Prevention. 2017;22(4):260.
  95. 95. Steinman RM. Decisions about dendritic cells: past, present, and future. Annual review of immunology. 2012;30:1-22.
  96. 96. Vivier E, Tomasello E, Baratin M, Walzer T, Ugolini S. Functions of natural killer cells. Nature immunology. 2008;9(5):503.
  97. 97. Kazemi A, Agha Alinejad H, Eslami R, Ehsan P, Baghaei R, Dabaghzadeh R, et al. Investigating the Effect of Endurance Training on Tumor Level of IL-8 and Serum Level of IL-17 in Female Mice with Breast Cancer. Journal of Fasa University of Medical Sciences. 2015;5(3):347-55. [In Persian].
  98. 98. Friedenreich CM, Neilson HK, Lynch BM. State of the epidemiological evidence on physical activity and cancer prevention. European journal of cancer. 2010;46(14):2593-604.
  99. 99. Shamsi MM, Chekachak S, Soudi S, Quinn L, Ranjbar K, Chenari J, et al. Combined effect of aerobic interval training and selenium nanoparticles on expression of IL-15 and IL-10/TNF-α ratio in skeletal muscle of 4T1 breast cancer mice with cachexia. Cytokine. 2017;90:100-8.
  100. 100. Ghorbanian B, Montazeri V, Rostami F, Khanvari T. Effect of combined exercises (aerobic-pilates) on the serum level of interleukin 10 and blood platelets in women with breast cancer. The Iranian Journal of Obstetrics, Gynecology and Infertility. 2021;24(1):9-17. [In Persian].
  101. 101. Alizadeh AM, Isanejad A, Sadighi S, Mardani M, Hassan ZM. High-intensity interval training can modulate the systemic inflammation and HSP70 in the breast cancer: a randomized control trial. Journal of cancer research and clinical oncology. 2019;145(10):2583-93.
  102. 102. Grivennikov SI, Karin M. Inflammatory cytokines in cancer: tumour necrosis factor and interleukin 6 take the stage. Annals of the rheumatic diseases. 2011;70(Suppl 1):i104-i8.
  103. 103. Taniguchi K, Karin M, editors. IL-6 and related cytokines as the critical lynchpins between inflammation and cancer. Seminars in immunology; 2014: Elsevier.
  104. 104. Liou G-Y, Storz P. Reactive oxygen species in cancer. Free radical research. 2010;44(5):479-96.
  105. 105. Papadopoulos E, Santa Mina D. Can we HIIT cancer if we attack inflammation? Cancer Causes & Control. 2018:1-5.
  106. 106. Mitranun W, Deerochanawong C, Tanaka H, Suksom D. Continuous vs interval training on glycemic control and macro‐and microvascular reactivity in type 2 diabetic patients. Scandinavian journal of medicine & science in sports. 2014;24(2).
  107. 107. Barrett CW, Ning W, Chen X, Smith JJ, Washington MK, Hill KE, et al. Tumor suppressor function of the plasma glutathione peroxidase gpx3 in colitis-associated carcinoma. Cancer research. 2013;73(3):1245-55.
  108. 108. Qi X, Ng KTP, Lian QZ, Liu XB, Li CX, Geng W, et al. Clinical significance and therapeutic value of glutathione peroxidase 3 (GPx3) in hepatocellular carcinoma. Oncotarget. 2014;5(22):11103.
  109. 109. Godsland IF. Insulin resistance and hyperinsulinaemia in the development and progression of cancer. Clinical Science. 2010;118(5):315-32.
  110. 110. Jelleyman C, Yates T, O'Donovan G, Gray LJ, King JA, Khunti K, et al. The effects of high‐intensity interval training on glucose regulation and insulin resistance: a meta‐analysis. Obesity reviews. 2015;16(11):942-61.
  111. 111. Hood MS, Little JP, Tarnopolsky MA, Myslik F, Gibala MJ. Low-volume interval training improves muscle oxidative capacity in sedentary adults. Medicine and science in sports and exercise. 2011;43(10):1849-56.
  112. 112. Gavin TP, Wagner PD. Effect of short-term exercise training on angiogenic growth factor gene responses in rats. Journal of Applied Physiology. 2001;90(4):1219-26.
  113. 113. Taheri H, Nourshahi M, Ranjbar K. Response of vascular endothelial growth factor to exhaustive Exercise and its relationship with VO2max. Journal of Sport Biosciences. 2010;7:59-75. [In Persian].
  114. 114. Christopoulos A, Ahn SM, Klein JD, Kim S. Biology of vascular endothelial growth factor and its receptors in head and neck cancer: beyond angiogenesis. Head & neck. 2011;33(8):1220-9.
  115. 115. TaheriChadorneshin H, Nourshahi M. A Review of Response of Angiogenic and Angiostatic Factors to Exercise. The Horizon of Medical Sciences. 2017;23(4):331-8. [In Persian].
  116. 116. Nourshahi M, Taheri H, Ranjbar K. The stimulus of angiogenesis during exercise and physical activity. Quarterly of the Horizon of Medical Sciences. 2013;18:286-96. [In Persian].
  117. 117. Roy S, Khanna S, Sen CK. Redox regulation of the VEGF signaling path and tissue vascularization: Hydrogen peroxide, the common link between physical exercise and cutaneous wound healing. Free Radical Biology and Medicine. 2008;44(2):180-92.
  118. 118. Ushio-Fukai M, Nakamura Y. Reactive oxygen species and angiogenesis: NADPH oxidase as target for cancer therapy. Cancer letters. 2008;266(1):37-52.
  119. 119. Ahmadian M, Azizbeigi K, Delphan M, Atashak S. The Effect of High Intensity Interval Training on STAT-3 and Angiopoietin-1 Gene Expression, and tie-2 Protein in Mice with Breast Cancer. Iranian Journal of Breast Diseases. 2018;11(1):37-46. [In Persian].
  120. 120. Thompson HJ, Jiang W, Zhu Z. Candidate mechanisms accounting for effects of physical activity on breast carcinogenesis. IUBMB life. 2009;61(9):895-901.
  121. 121. Lowery AJ, Miller N, McNeill RE, Kerin MJ. MicroRNAs as prognostic indicators and therapeutic targets: potential effect on breast cancer management. Clinical Cancer Research. 2008;14(2):360-5.
  122. 122. Shi M, Guo N. MicroRNA expression and its implications for the diagnosis and therapeutic strategies of breast cancer. Cancer treatment reviews. 2009;35(4):328-34.
  123. 123. Rafiei MM, Soltani R, Kordi MR, Nouri R, Gaeini AA. Gene expression of angiogenesis and apoptotic factors in female BALB/c mice with breast cancer after eight weeks of aerobic training. Iranian Journal of Basic Medical Sciences. 2021;24(9).
  124. 124. Kuehbacher A, Urbich C, Dimmeler S. Targeting microRNA expression to regulate angiogenesis. Trends in pharmacological 2008;29(1):12-5.
  125. 125. Nasiri Ivanaki M, Farsi S, Ghaedi H. Investigation of the Effect of High-Intensity Interval Training (HIIT) on the Expression of the Genes miR-126, miR-296, HGS and VEGF-A Protein Levels in Tumor Tissue in Female Mice. Journal of Fasa University of Medical Sciences. 2021;10(4):0. [In Persian].
آمار
تعداد مشاهده مقاله: 2,053
تعداد دریافت فایل اصل مقاله: 1,410


سامانه مدیریت نشریات علمی. قدرت گرفته از سیناوب