آمار
| تعداد نشریات | 5 |
| تعداد شماره‌ها | 117 |
| تعداد مقالات | 1,388 |
| تعداد مشاهده مقاله | 1,403,818 |
| تعداد دریافت فایل اصل مقاله | 1,371,524 |
تاثیر هشت هفته تمرین یوگا بر سطوح سرمی BDNF زنان مبتلا به مولتیپل اسکلروزیس | ||
| مطالعات کاربردی تندرستی در فیزیولوژی ورزش | ||
| مقاله 11، دوره 4، شماره 2، مهر 1396، صفحه 81-88 اصل مقاله (942.48 K) | ||
| نوع مقاله: مقاله پژوهشی Released under (CC BY-NC 4.0) license I Open Access I | ||
| شناسه دیجیتال (DOI): 10.22049/jassp.2019.26568.1232 | ||
| نویسندگان | ||
| سمانه سعدی زاده1؛ سید محسن آوندی* 2؛ محسن ابراهیمی2 | ||
| 1کارشناس ارشد فیزیولوژی ورزش، دانشکدهی علوم انسانی، دانشگاه سمنان، ایران | ||
| 2استادیار گروه فیزیولوژی ورزش، دانشکدهی علوم انسانی، دانشگاه سمنان، ایران | ||
| چکیده | ||
| مولتیپل اسکلروزیس (MS) بیماری التهابی است که باعث آسیب غلاف میلین سلول‌های عصبی در مغز و نخاع می گردد. عامل نورون زایی مشتق از مغز (BDNF) نقش حیاتی در بقای نورون‌ها، آکسون و میلین سازی مجدد دارد. هدف از پژوهش حاضر بررسی تأثیر هشت هفته تمرین یوگا بر سطوح سرمی BDNF در زنان مبتلا به مولتیپل اسکلروزیس بود. شانزده زن مبتلا به MS (با میانگین سن 7/7±8/37 سال، قد 4/7±7/161 سانتی‌متر و وزن 2/18±7/70 کیلوگرم) با نمره مقیاس ناتوانی جسمانی کروتزگه (EDSS) کمتر از 4 انتخاب و به‌طور تصادفی به دو گروه تمرین یوگا (8 نفر) و کنترل (8 نفر) تقسیم شدند. گروه یوگا به مدت هشت هفته و سه جلسه در هفته به تمرین یوگا پرداختند. گروه کنترل صرفا فعالیت روزمره خود را انجام دادند. نمونه‌های خونی 48 ساعت قبل و بعد از دوره تمرین جمع‌آوری گردید. سطوح سرمی BDNF به روش الایزا ارزیابی شد. تجزیه و تحلیل آماری از طریق آزمون t وابسته و مستقل در سطح معناداری 05/0≥P انجام گرفت. نتایج این پژوهش نشان داد که تمرین یوگا سطوح سرمی BDNF را در زنان مبتلا به MS افزایش می دهد، در حالی که سطوح سرم BDNF در گروه کنترل کاهش یافته بود. در کل نتایج نشان داد، مقدار BDNF سرمی بیماران MS در پاسخ به تمرین یوگا افزایش می یابد که انتظار می رود در فرآیند ترمیم و حفظ اعصاب مفید باشد. | ||
| کلیدواژه‌ها | ||
| مولتیپل اسکلروزیس؛ فاکتور نورون زایی مشتق از مغز؛ یوگا | ||
| مراجع | ||
4. Ahrendsen, J. T., & Macklin, W. (2013). Signaling mechanisms regulating myelination in the central nervous system. Neurosci Bull, 29(2), 199-215. doi: 10.1007/s12264-013-1322-2.
5. Azoulay, David, Vachapova, Veronika, Shihman, Boris, Miler, Ariel, & Karni, Arnon. (2005). Lower brain-derived neurotrophic factor in serum of relapsing remitting MS: reversal by glatiramer acetate. Journal of neuroimmunology, 167(1), 215-218.
6. Bansi, J, Bloch, W, Gamper, U, & Kesselring, J. (2012). Training in MS: influence of two different endurance training protocols (aquatic versus overland) on cytokine and neurotrophin concentrations during three week randomized controlled trial. Multiple Sclerosis Journal, 1352458512458605.
7. Bansi, J., Bloch, W., Gamper, U., & Kesselring, J. (2013). Training in MS: influence of two different endurance training protocols (aquatic versus overland) on cytokine and neurotrophin concentrations during three week randomized controlled trial. Mult Scler, 19(5), 613-621. doi: 10.1177/1352458512458605
8. Barnes, Patricia M., Powell-Griner, Eve, McFann, Kim, & Nahin, Richard L. (2004). Complementary and alternative medicine use among adults: United
States, 2002. Seminars in Integrative Medicine, 2(2), 54-71. doi: 10.1016/j.sigm.2004.07.003.
9. Bernardes, Danielle, Oliveira-Lima, Onésia Cristina, da Silva, Thiago Vitarelli, Faraco, Camila Cristina Fraga, Leite, Hércules Ribeiro, Juliano, Maria Aparecida,.. Orian, Jacqueline M. (2013). Differential brain and spinal cord cytokine and BDNF levels in experimental autoimmune encephalomyelitis are modulated by prior and regular exercise. Journal of neuroimmunology, 264(1), 24-34.
10. BIRNBAUM, #160, Gary, LEIST, #160, P., Thomas,.. Ranjan. (2007). Pathogenesis of axonal and neuronal damage in multiple sclerosis. Hagerstown, MD, ETATS-UNIS: Lippincott Williams & Wilkins.
11. Black, P. H. (1994). Central nervous system-immune system interactions: psychoneuroendocrinology of stress and its immune consequences. Antimicrob Agents Chemother, 38(1), 1-6.
12. Brown, Richard P, & Gerbarg, Patricia L. (2005). Sudarshan Kriya yogic breathing in the treatment of stress, anxiety, and depression: part I-neurophysiologic model. Journal of Alternative & Complementary Medicine, 11(1), 189-201.
13. Castellano, V., & White, L. J. (2008). Serum brain-derived neurotrophic factor response to aerobic exercise in multiple sclerosis. Journal of the neurological sciences, 269(1), 85-91.
14. Dalgas, U, Stenager, Egon, & Ingemann-Hansen, Thorsten. (2007). Multiple sclerosis and physical exercise: recommendations for the application of resistance-, endurance-and combined training. Multiple sclerosis.
15. Dutta, Ranjan, & Trapp, Bruce D. (2007). Pathogenesis of axonal and neuronal damage in multiple sclerosis. Neurology, 68(22 suppl 3), S22-S31.
16. Frank, R., & Larimore, J. (2015). Yoga as a method of symptom management in multiple sclerosis. Front Neurosci, 9, 133. doi: 10.3389/fnins.2015.00133.
17. Gold, S. M., Schulz, K. H., Hartmann, S., Mladek, M., Lang, U. E., Hellweg, R.,.. Heesen, C. (2003). Basal serum levels and reactivity of nerve growth factor and brain-derived neurotrophic factor to standardized acute exercise in multiple sclerosis and controls. J Neuroimmunol, 138(1-2), 99-105.
18. Guner, Senem, & Inanici, Fatma. (2015). Yoga therapy and ambulatory multiple sclerosis assessment of gait analysis parameters, fatigue and balance. Journal of bodywork and movement therapies, 19(1), 72-81.
19. Kalinowska-Lyszczarz, A., & Losy, J. (2012). The role of neurotrophins in multiple sclerosis-pathological and clinical implications. Int J Mol Sci, 13(10), 13713-13725. doi: 10.3390/ijms131013713.
20. Lee, M., Moon, W., & Kim, J. (2014). Effect of yoga on pain, brain-derived neurotrophic factor, and serotonin in premenopausal women with chronic low back pain. Evid Based Complement Alternat Med, 2014, 203173. doi: 10.1155/2014/203173.
21. Mandel, A. L., Ozdener, H., & Utermohlen, V. (2009). Identification of pro- and mature brain-derived neurotrophic factor in human saliva. Arch Oral Biol, 54(7), 689-695. doi: 10.1016/j.archoralbio.2009.04.005.
22. Masoudnejad, M, Kh, Ebrahim, & Shirvani, H. (2012). Impactof Selected Combinations of Training on Muscle Strength and Motor Function in Women with Multiple Sclerosis (MS). Sports Physiology, 16, 81-96.
23. McGuinness, Sandra D, & Peters, Sharon. (1999). The diagnosis of multiple sclerosis: Peplau's Interpersonal Relations Model in practice. Rehabilitation Nursing, 24(1), 30-33.
24. Milo, Ron, & Kahana, Esther. (2010). Multiple sclerosis: geoepidemiology, genetics and the environment. Autoimmunity reviews, 9(5), A387-A394.
25. Moghadasi, mehrzad, edalat manesh, mohammad amin, moeini, aida, & namatollahzadeh, mohadeseh. (2015). Effects of eight weeks resistance training on brain derived neurotrophic factor in female patients with multiple sclerosis. koomesh, 17(1), 152-159.
26. Muhammad, Charlene Marie, & Moonaz, Steffany Haaz. (2014). Yoga as Therapy for Neurodegenerative Disorders: A Case Report of Therapeutic Yoga for Adrenomyeloneuropathy. Integrative Medicine: A Clinician's Journal, 13(3), 33.
27. Murray, P. S., & Holmes, P. V. (2011). An overview of brain-derived neurotrophic factor and implications for excitotoxic vulnerability in the hippocampus. International journal of peptides, 2011.
28. Najafidoulatabad, S., Mohebbi, Z., & Nooryan, K. (2014). Yoga effects on physical activity and sexual satisfaction among the Iranian women with multiple sclerosis: a randomized controlled trial. Afr J Tradit Complement Altern Med, 11(5), 78-82.
29. Nakahara, Jin, Maeda, Michiko, Aiso, Sadakazu, & Suzuki, Norihiro. (2012). Current concepts in multiple sclerosis: autoimmunity versus oligodendrogliopathy. Clinical reviews in allergy & immunology, 42(1), 26-34.
30. Neeper, S. A., Gómez-Pinilla, F., Choi, J., & Cotman, C. W. (1996). Physical activity increases mRNA for brain-derived neurotrophic factor and nerve growth factor in rat brain. Brain research, 726(1), 49-56.
31. Patterson, S. L., Abel, T., Deuel, T. A., Martin, K. C., Rose, J. C., & Kandel, E. R. (1996). Recombinant BDNF rescues deficits in basal synaptic transmission and hippocampal LTP in BDNF knockout mice. Neuron, 16(6), 1137-1145.
32. Pencea, V., Bingaman, K. D., Wiegand, S. J., & Luskin, M. B. (2001). Infusion of brain-derived neurotrophic factor into the lateral ventricle of the adult rat leads to new neurons in the parenchyma of the striatum, septum, thalamus, and hypothalamus. J Neurosci, 21(17), 6706-6717.
33. Perry, V Hugh, & Anthony, DC. (1999). Axon damage and repair in multiple sclerosis. Philosophical Transactions of the Royal Society of London B: Biological Sciences, 354(1390), 1641-1647.
34. Reichardt, Louis F. (2006). Neurotrophin-regulated signalling pathways. Philosophical Transactions of the Royal Society B: Biological Sciences, 361(1473), 1545-1564. doi: 10.1098/rstb.2006.1894.
35. Rezaee, Zeinab, Marandi, Sayed Mohammad, Ghaedi, Kamran, & Esfarjani, Fahimeh. (2015). A Review on The Function and Molecular Structure of Neurotrophins. Genetics in the 3rd millennium, 12(4), 3806-3822.
36. Rogers, Kim A, & MacDonald, Megan. (2015). Therapeutic Yoga: Symptom Management for Multiple Sclerosis. The Journal of Alternative and Complementary Medicine, 21(11), 655-659.
37. Schaaf, Marcel JM, Hoetelmans, Rob WM, de Kloet, E Ronald, & Vreugdenhil, Erno. (1997). Corticosterone regulates expression of BDNF and trkB but not NT‐3 and trkC mRNA in the rat hippocampus. Journal of neuroscience research, 48(4), 334-341.
38. Schulz, K. H., Gold, S. M., Witte, J., Bartsch, K., Lang, U. E., Hellweg, R.,.. Heesen, C. (2004). Impact of aerobic training on immune-endocrine parameters, neurotrophic factors, quality of life and coordinative function in multiple sclerosis. J Neurol Sci, 225(1-2), 11-18. doi: 10.1016/j.jns.2004.06.009.
39. Shabani, Mohsen, Hovanloo, Fariborz, Ebrahim, Khosro, & Hedayati, Mehdi. (2014). The effect of acute resistance exercise on BDNF, IGF-1 and IGFBP-3 in the elderly. Iranian Journal of Ageing, 9(3), 218-226.
40. Sorenson, M, Jason, L, Peterson, J, Herrington, J, & Mathews, H. (2014). Brain derived neurotrophic factor is decreased in chronic fatigue syndrome and multiple sclerosis. J Neurol Neurophysiol S, 12, S2-013.
41. Streeter, Chris C., Whitfield, Theodore H., Owen, Liz, Rein, Tasha, Karri, Surya K., Yakhkind, Aleksandra,.. Jensen, J. Eric. (2010). Effects of Yoga Versus Walking on Mood, Anxiety, and Brain GABA Levels: A Randomized Controlled MRS Study. Journal of Alternative and Complementary Medicine, 16(11), 1145-1152. doi: 10.1089/acm.2010.0007.
42. Sung, Paul S. (2014). New Perspective: Outcome Measurement Indices for Yoga Therapy. Journal of Yoga & Physical Therapy, 2014.
43. Villien, F., Yu, M., Barthelemy, P., & Jammes, Y. (2005). Training to yoga respiration selectively increases respiratory sensation in healthy man. Respir Physiol Neurobiol, 146(1), 85-96. doi: 10.1016/j.resp.2004.11.010.
44. Waschbisch, A., Wenny, I., Tallner, A., Schwab, S., Pfeifer, K., & Maurer, M. (2012). Physical activity in multiple sclerosis: a comparative study of vitamin D, brain-derived neurotrophic factor and regulatory T cell populations. Eur Neurol, 68(2), 122-128.
45. Xiao, J., Wong, A. W., Willingham, M. M., Kaasinen, S. K., Hendry, I. A., Howitt, J.,.. Murray, S. S. (2009). BDNF exerts contrasting effects on peripheral myelination of NGF-dependent and BDNF-dependent DRG neurons. J Neurosci, 29(13), 4016-4022. doi: 10.1523/jneurosci.3811-08.2009.
46. Zafra, F., Castren, E., Thoenen, H., & Lindholm, D. (1991). Interplay between glutamate and gamma-aminobutyric acid transmitter systems in the physiological regulation of brain-derived neurotrophic factor and nerve growth factor synthesis in hippocampal neurons. Proceedings of the National Academy of Sciences, 88(22), 10037-10041. | ||
|
آمار تعداد مشاهده مقاله: 1,140 تعداد دریافت فایل اصل مقاله: 831 |
||