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تاثیر هشت هفته تمرین یوگا بر سطوح سرمی BDNF زنان مبتلا به مولتیپل اسکلروزیس | ||
| مطالعات کاربردی تندرستی در فیزیولوژی ورزش | ||
| مقاله 11، دوره 4، شماره 2، مهر 1396، صفحه 81-88 اصل مقاله (942.48 K) | ||
| نوع مقاله: مقاله پژوهشی Released under (CC BY-NC 4.0) license I Open Access I | ||
| شناسه دیجیتال (DOI): 10.22049/jassp.2019.26568.1232 | ||
| نویسندگان | ||
| سمانه سعدی زاده1؛ سید محسن آوندی* 2؛ محسن ابراهیمی2 | ||
| 1کارشناس ارشد فیزیولوژی ورزش، دانشکدهی علوم انسانی، دانشگاه سمنان، ایران | ||
| 2استادیار گروه فیزیولوژی ورزش، دانشکدهی علوم انسانی، دانشگاه سمنان، ایران | ||
| چکیده | ||
| مولتیپل اسکلروزیس (MS) بیماری التهابی است که باعث آسیب غلاف میلین سلول‌های عصبی در مغز و نخاع می گردد. عامل نورون زایی مشتق از مغز (BDNF) نقش حیاتی در بقای نورون‌ها، آکسون و میلین سازی مجدد دارد. هدف از پژوهش حاضر بررسی تأثیر هشت هفته تمرین یوگا بر سطوح سرمی BDNF در زنان مبتلا به مولتیپل اسکلروزیس بود. شانزده زن مبتلا به MS (با میانگین سن 7/7±8/37 سال، قد 4/7±7/161 سانتی‌متر و وزن 2/18±7/70 کیلوگرم) با نمره مقیاس ناتوانی جسمانی کروتزگه (EDSS) کمتر از 4 انتخاب و به‌طور تصادفی به دو گروه تمرین یوگا (8 نفر) و کنترل (8 نفر) تقسیم شدند. گروه یوگا به مدت هشت هفته و سه جلسه در هفته به تمرین یوگا پرداختند. گروه کنترل صرفا فعالیت روزمره خود را انجام دادند. نمونه‌های خونی 48 ساعت قبل و بعد از دوره تمرین جمع‌آوری گردید. سطوح سرمی BDNF به روش الایزا ارزیابی شد. تجزیه و تحلیل آماری از طریق آزمون t وابسته و مستقل در سطح معناداری 05/0≥P انجام گرفت. نتایج این پژوهش نشان داد که تمرین یوگا سطوح سرمی BDNF را در زنان مبتلا به MS افزایش می دهد، در حالی که سطوح سرم BDNF در گروه کنترل کاهش یافته بود. در کل نتایج نشان داد، مقدار BDNF سرمی بیماران MS در پاسخ به تمرین یوگا افزایش می یابد که انتظار می رود در فرآیند ترمیم و حفظ اعصاب مفید باشد. | ||
| کلیدواژه‌ها | ||
| مولتیپل اسکلروزیس؛ فاکتور نورون زایی مشتق از مغز؛ یوگا | ||
| مراجع | ||
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