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تأثیر 8 هفته تمرین تناوبی با شدت بالا (HIIT) بر مقادیر سرمی آیریزین، FGF21 و شاخصهای گلایسمی در زنان دیابتی نوع 2 | ||
مطالعات کاربردی تندرستی در فیزیولوژی ورزش | ||
مقاله 3، دوره 6، شماره 2، مهر 1398، صفحه 17-24 اصل مقاله (995.21 K) | ||
نوع مقاله: مقاله پژوهشی Released under (CC BY-NC 4.0) license I Open Access I | ||
شناسه دیجیتال (DOI): 10.22049/jassp.2019.26337.1184 | ||
نویسندگان | ||
لیلا علیزاده1؛ اصغر توفیقی2؛ جواد طلوعی آذر* 3 | ||
1کارشناس ارشد فیزیولوژی ورزشی، گروه فیزیولوژی ورزشی، دانشکده علوم ورزشی، دانشگاه ارومیه، ارومیه، ایران. | ||
2دانشیار فیزیولوژی ورزشی، گروه فیزیولوژی ورزشی، دانشکده علوم ورزشی، دانشگاه ارومیه، ارومیه، ایران | ||
3استادیار فیزیولوژی ورزشی، گروه فیزیولوژی ورزشی، دانشکده علوم ورزشی، دانشگاه ارومیه، ارومیه، ایران. | ||
چکیده | ||
هدف: در اثر فعالیت ورزشی، مایوکاینهایی نظیر آیریزین و FGF21 با میانجیگری اثرات ضد التهابی خود، در مهار پیشرفت مقاومت به انسولین ناشی از دیابت نوع 2 موثر میباشند. از این رو، هدف پژوهش حاضر بررسی تأثیر 8 هفته HIIT بر مقادیر سرمی آیریزین، FGF21و شاخصهای گلایسمی در زنان دیابتی نوع 2 بود. روش شناسی: 20 زن مبتلاء به دیابت نوع 2 (سن: 3/55 سال و BMI: 09/27 کیلوگرم بر متر مربع) به طور تصادفی در دو گروه 10 نفری HIIT و کنترل تقسیمبندی شدند. برنامه تمرین HIIT به مدت 8 هفته، 3 جلسه در هفته و با شدت 85 ـ 80 درصد ضربان قلب بیشینه اجرا شد. پیش و پس از اتمام برنامه تمرینی از دو گروه در حالت ناشتا نمونهگیری خونی به عمل آمد تا مقادیر سرمی آیریزین، FGF21و شاخصهای گلایسمی اندازهگیری شود. دادههای پژوهش با استفاده از آزمون آماری t همبسته و tمستقل تجزیه و تحلیل شدند (05/0 >p). یافته ها: HIIT به طور معناداری مقادیر سرمی آیریزین و FGF21 زنان دیابتی نوع 2 را بعد از 8 هفته افزایش (001/0p=) و HBA1c (003/0p=)، گلوکز و مقاومت به انسولین (006/0p=) را کاهش داد. بین گروه تمرین و کنترل در مقادیر FGF21، آیریزین و شاخصهای گلایسمی تفاوت معناداری وجود داشت (001/0p=). نتیجه گیری: بر اساس نتایج پژوهش حاضر، به نظر میرسد HIITاز طریق تحریک ترشح مایوکاینهایی نظیر آیریزین و FGF21در کنترل هومئوستاز قند و مقاومت به انسولین بدن موثر باشد. با وجود این، با توجه به تاثیر آیریزین بر تغییرات بافت چربی سفید و قهوهای، بررسی تغییرات آدیپوکاینها در کنار FGF21 و آیریزین عضلانی با تمرینات HIIT قابل توجه میباشد. | ||
کلیدواژهها | ||
تمرین تناوبی با شدت بالا (HIIT)؛ آیریزین؛ FGF21؛ شاخصهای گلایسمی؛ زنان دیابتی نوع 2 | ||
مراجع | ||
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