اثرات هشت هفته تمرین هوازی و رزوراترول بر بیان ژن‌های دخیل در ترموژنز و پروفایل لیپیدی در موش‌های نر نژاد C57BL/6

1. Santos SHS, Andrade JMO. Angiotensin 1–7: A peptide for preventing and treating metabolic syndrome. Peptides. 2014;59:34-41.

2. Baglioni S, Cantini G, Poli G, Francalanci M, Squecco R, Di Franco A, et al. Functional differences in visceral and subcutaneous fat pads originate from differences in the adipose stem cell. PLoS one. 2012;7(5):e36569.

3. Andrade JMO, Frade ACM, Guimaraes JB, Freitas KM, Lopes MTP, Guimarães ALS, et al. Resveratrol increases brown adipose tissue thermogenesis markers by increasing SIRT1 and energy expenditure and decreasing fat accumulation in adipose tissue of mice fed a standard diet. European journal of nutrition. 2014;53(7):1503-10.

4. Boström P, Wu J, Jedrychowski MP, Korde A, Ye L, Lo JC, et al. A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis. Nature. 2012;481(7382):463-8.

5. Castillo-Quan JI. From white to brown fat through the PGC-1α-dependent myokine irisin: implications for diabetes and obesity. Disease models & mechanisms. 2012;5(3):293-5.

6. Roca-Rivada A, Castelao C, Senin LL, Landrove MO, Baltar J, Crujeiras AB, et al. FNDC5/irisin is not only a myokine but also an adipokine. PloS one. 2013;8(4):e60563.

7. Khalafi M, Shabkhiz F, Azali Alamdari K, Bakhtiyari A. irisin response to two types of exercise training in type 2 diabetic male rats. Journal of Arak University of Medical Sciences. 2016;19(6):37-45. [In Persian]

8. Stanford KI, Goodyear LJ. Exercise regulation of adipose tissue. Adipocyte. 2016;5(2):153-62.

9. Baur JA, Pearson KJ, Price NL, Jamieson HA, Lerin C, Kalra A, et al. Resveratrol improves health and survival of mice on a high-calorie diet. Nature. 2006;444(7117):337-42.

10. Olas B, Wachowicz B, Saluk-Juszczak J, Zieliński T, Kaca W, Buczyński A. Antioxidant activity of resveratrol in endotoxin-stimulated blood platelets. Cell biology and toxicology. 2001;17(2):117-25.

11. Borra MT, Smith BC, Denu JM. Mechanism of human SIRT1 activation by resveratrol. Journal of Biological Chemistry. 2005;280(17):17187-95.

12. Houtkooper RH, Pirinen E, Auwerx J. Sirtuins as regulators of metabolism and healthspan. Nature reviews Molecular cell biology. 2012;13(4):225-38.

13. Satoh A, Stein L, Imai S. The role of mammalian sirtuins in the regulation of metabolism, aging, and longevity. Histone Deacetylases: the Biology and Clinical Implication. 2011:125-62.

14. Huang Y, Lu J, Zhan L, Wang M, Shi R, Yuan X, et al. Resveratrol-induced Sirt1 phosphorylation by LKB1 mediates mitochondrial metabolism. Journal of Biological Chemistry. 2021;297(2).

15. Alberdi G, Rodríguez VM, Miranda J, Macarulla MT, Churruca I, Portillo MP. Thermogenesis is involved in the body-fat lowering effects of resveratrol in rats. Food chemistry. 2013;141(2):1530-5.

16. Lagouge M, Argmann C, Gerhart-Hines Z, Meziane H, Lerin C, Daussin F, et al. Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1α. Cell. 2006;127(6):1109-22.

17. Kazeminasab F, Marandi SM, Ghaedi K, Safaeinejad Z, Esfarjani F, Nasr-Esfahani MH. A comparative study on the effects of high-fat diet and endurance training on the PGC-1α-FNDC5/irisin pathway in obese and nonobese male C57BL/6 mice. Applied physiology, nutrition, and metabolism. 2018;43(7):651-62.

18. Powers SK, Criswell D, Lawler J, Martin D, Lieu F-K, Ji LL, et al. Rigorous exercise training increases superoxide dismutase activity in ventricular myocardium. American Journal of Physiology-Heart and Circulatory Physiology. 1993;265(6):H2094-H8.

19. Kazeminasab F, Marandi SM, Shirkhani S, Sheikhanian Poor A, Ghaedi K. The Effect of 8 Weeks Aerobic Exercise on LXRa, PEPCK, and G6PC2 mRNA in Obese Prediabetic Mice. Sport Physiology. 2020;12(48):17-38. [In Persian]

20. Um J-H, Park S-J, Kang H, Yang S, Foretz M, McBurney MW, et al. AMP-activated protein kinase–deficient mice are resistant to the metabolic effects of resveratrol. Diabetes. 2010;59(3):554-63.

21. Moussa C, Hebron M, Huang X, Ahn J, Rissman RA, Aisen PS, et al. Resveratrol regulates neuro-inflammation and induces adaptive immunity in Alzheimer’s disease. Journal of neuroinflammation. 2017;14(1):1-10.

22. Andrade JMO, Barcala-Jorge AS, Batista-Jorge GC, Paraíso AF, de Freitas KM, de Farias Lelis D, et al. Effect of resveratrol on expression of genes involved thermogenesis in mice and humans. Biomedicine & Pharmacotherapy. 2019;112:108634.

23. Shirkhani S, Marandi SM, Kazeminasab F, Esmaeili M, Ghaedi K, Esfarjani F, et al. Comparative studies on the effects of high-fat diet, endurance training and obesity on Ucp1 expression in male C57BL/6 mice. Gene. 2018;676:16-21.

24. Raschke S, Elsen M, Gassenhuber H, Sommerfeld M, Schwahn U, Brockmann B, et al. Evidence against a beneficial effect of irisin in humans. PloS one. 2013;8(9):e73680.

25. Jimenez-Gomez Y, Mattison JA, Pearson KJ, Martin-Montalvo A, Palacios HH, Sossong AM, et al. Resveratrol improves adipose insulin signaling and reduces the inflammatory response in adipose tissue of rhesus monkeys on high-fat, high-sugar diet. Cell metabolism. 2013;18(4):533-45.

26. Fiori JL, Shin Y-K, Kim W, Krzysik-Walker SM, González-Mariscal I, Carlson OD, et al. Resveratrol prevents β-cell dedifferentiation in nonhuman primates given a high-fat/high-sugar diet. Diabetes. 2013;62(10):3500-13.

27. Kaeberlein M, McDonagh T, Heltweg B, Hixon J, Westman EA, Caldwell SD, et al. Substrate-specific activation of sirtuins by resveratrol. Journal of Biological Chemistry. 2005;280(17):17038-45.

28. Zheng X, Ai H, Yuan S, Cao H, Liang H, Weng J, et al. Effect of SIRT1 deficiency on function of brown adipose tissue in obese mice. Zhonghua yi xue za zhi. 2016;96(23):1859-62.

29. Wang S, Liang X, Yang Q, Fu X, Zhu M, Rodgers B, et al. Resveratrol enhances brown adipocyte formation and function by activating AMP‐activated protein kinase (AMPK) α1 in mice fed high‐fat diet. Molecular nutrition & food research. 2017;61(4):1600746.

30. Jørgensen SB, Richter EA, Wojtaszewski JF. Role of AMPK in skeletal muscle metabolic regulation and adaptation in relation to exercise. The Journal of physiology. 2006;574(1):17-31.

31. Marcinko K, Steinberg GR. The role of AMPK in controlling metabolism and mitochondrial biogenesis during exercise. Experimental physiology. 2014;99(12):1581-5.

32. Richter EA, Ruderman NB. AMPK and the biochemistry of exercise: implications for human health and disease. Biochemical Journal. 2009;418(2):261-75.

33. Qiang L, Wang L, Kon N, Zhao W, Lee S, Zhang Y, et al. Brown remodeling of white adipose tissue by SirT1-dependent deacetylation of Pparγ. Cell. 2012;150(3):620-32.